Prevalence of hypertriglyceridemia in cardiac patients and their clinical and demographic characteristics

• Alexander V. Shomin
• Elena K. Serezhina
• Andrey G. Obrezan

Abstract

Hypertriglyceridemia is a rather relevant and discussed residual risk factor for the development of atherosclerosis-associated cardiovascular pathology at present. The study of the prevalence, clinical and demographic characteristics of patients with this lipid spectrum disorder is of great scientific and practical interest in modern cardiology.

The aim of the research was to study the hypertriglyceridemia’s prevalence of in the population of cardiac patients 18–90 years old and assessment of the clinical and demographic characteristics of subjects with hypertriglyceridemia.

Material and methods. The sample included 850 cardiac patients aged 18–90 years. Clinical diagnoses were established on the basis of case histories, laboratory test results and anthropometric indicators.

Results. The prevalence of hypertriglyceridemia in the subjects studied was 58.8% (500 patients). This dyslipidemia was more common among men than among women in all age groups except the elderly. Hypertriglyceridemia was more common in middle age. Men had a larger waist circumference compared to the female population (p<0.001) with this lipid spectrum disorder. Often associated with triglyceride metabolism disorders are: metabolic syndrome, carbohydrate metabolism disorders, arterial hypertension, left ventricular hypertrophy, hypercholesterolemia, increased: low-density lipoproteins, very low-density lipoproteins, non-high-density lipoprotein cholesterol, residual cholesterol and atherogenicity coefficient. In the group of the carbohydrate metabolism disorders, the most common is impaired fasting glycemia (54.3%). Men were characterized by higher degrees of hypertriglyceridemia (p=0.015).

Conclusion. The prevalence of hypertriglyceridemia was quite high, which indicates the high significance of this lipid metabolism disorder in the management of cardiac patients. Increased blood triglyceride levels were more common among men, when compared with women, and in the middle age group of male population. Higher degrees of hypertriglyceridemia were observed in the male population, which should be taken into account when managing this cohort of patients.

Keywords: hypertriglyceridemia; dyslipidemia; triglycerides; atherosclerosis

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