Assessment of the dynamics of quality of life in patients with chronic heart failure on the background of therapy

• Olanna T. Kotsoeva
• Vadim V. Tyrenko
• Andrew V. Koltsov
• David V. Bestaev
• Vasilii A. Kachnov

Abstract

The article presents the results of a five-year study of changes in the life quality of patients with chronic heart failure against the cardiac resynchronization therapy and optimal drug therapy background.

The aim of the study was to compare the results of assessing the life quality of patients with chronic heart failure against the cardiac resynchronization therapy and optimal drug therapy over a 5-year follow-up period background and to develop discriminant function equations to predict outcomes after 5 years of follow-up.

Material and methods. The study included 60 patients (1^st group – 30 patients who had a pacemaker implanted for cardiac resynchronization therapy, 2^nd group – 30 patients on the background of optimal drug therapy). The MLHFQ (Minnesota living with heart failure) questionnaire was used to assess the quality of life of patients. The assessment of quality of life indicators was carried out initially and after five years of observation. The survey results analysis was carried out using factor analysis of the correlation responses structure. Linear discriminant analysis was performed to predict whether objects belong to two groups (responders and nonresponders).

Results. In patients with chronic heart failure, five years after the start of cardiac resynchronization therapy, there was a statistically significant increase in the quality of life and improvement in their performance. It was revealed that in patients five years after the start of cardiac resynchronization therapy, the social status is mainly higher than the physical one. The importance of the emotional mood of patients with cardiac resynchronization therapy and drug therapy in the course of treatment and the strong influence of this mood on the outcome of treatment was revealed.

Conclusion. In patients with chronic heart failure, within five years after the start of cardiac resynchronization therapy, there was a statistically significant increase in the quality of life indicator, as well as the relationship of the psychological attitude of patients to the effectiveness of treatment. Taking into account this circumstance will allow the doctor, as a psychologist, to try to adjust the patient to the perception of treatment after the start of cardiac resynchronization therapy and drug therapy, to increase his adherence to treatment and life expectancy.

Keywords:chronic heart failure; quality of life; cardiac resynchronization therapy; drug therapy; quality of life questionnaire for CHF (MLHFQ)

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