Conceptual aspects of arterial hypertension treatment

• Zolotovskaia Irina A.
• Duplyakov Dmitriy V.

AbstractArterial hypertension сan lead to development of more than 60% cases of stroke and about 50% cases of coronary heart disease, due to which about 9.4 million deaths occur annually in the world. To reduce this indicator, it is necessary to determine meaningful moments in the drug choice for delivery of antihypertensive therapy in real-life' clinical practice settings for patients with hypertension and comorbid status. The authors believe that careful analysis of comorbidity with «pros» and «cons» characterization of long-term medication, with a step-by-step assessment of antihypertensive drugs proven benefits, will ensure consistent and competent treatment of arterial hypertension. In the article drugs of choice when initiating antihypertensive therapy, including cases with comorbidities (diabetes, diabetic nephropathy, liver dysfunction, cerebrovascular pathology, and effects of stroke), are represented. Necessity of taking into account phenotype of a patient with hypertension and timely correction of antihypertensive therapy in each clinical case is emphasized.

Keywords:arterial hypertension, population strategy, arterial blood pressure, cardiovascular complications, mortality, comorbidity

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