Clinical and pharmacological determinants of patients with hypertension older than 60 years in real clinical practice: results of the observation program GRANAT

• Zolotovskaia Irina A.
• Duplyakov Dmitriy V.
• Zyuzina Tatyana V.
• Davydkin Igor L.

Abstract

The aim of the study was a comprehensive study of comorbidity and medications use in patients with hypertension over the age of 60 years in real clinical practice.

Material and methods. The study, which was registered as a single-step observational program "Arterial Hypertension: main clinical and pharmacological determinants in patients over 60 years old" (acronym "GRANAT"), was conducted on the basis of 8 medical and preventive treatment institutions of Samara and Samara region using questionnaire method and chart review.

Results. The study included 460 patients: 201 (43.7%) men, 259 (56.3%) women, mean age - 76.72±8.08 years. Depending on the age all of them were divided into 2 groups: 1^st group (60-79 years), 2^nd group - ≥80 years. There were statistically significant differences in the form of higher incidence of diseases such as coronary heart disease, chronic brain ischemia, osteoporosis, glaucoma, Parkinson's disease, stroke in patients ≥80 years compared with the group of 60-79 years. It was also noted a significant number of prescribed drugs in patients of group 2 in accordance with each of the existing diseases.

Conclusion. Our data demonstrate multimorbidity of the population of patients with hypertension older than 60 years in real clinical practice, receiving a range of different drugs.

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