Prospects for managing patients with stable atherosclerosis

• Pavlova Tatyana V.
• Duplyakov Dmitriy V.
• Vorontsova Sofia A.
• Guseva G.N.

AbstractLong-term management of patients with stable atherosclerosis is regulated by current clinical guidelines, but until now some treatment aspects remain unclear. This paper presents applicability of combined anti-thrombotic (anti-platelet and anticoagulant) therapy, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors; brief review of randomized clinical trials examining efficacy and safety of these drugs is given; indications field are estimated; controversial issues of their administration are being looked at.

Keywords:atherosclerosis, ischemic heart disease, peripheral vascular disease, rivaroxaban, PCSK9, SGLT2

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