Association of subclinical left ventricular systolic dysfunction and kidney injury in patients with type 1 diabetes mellitus without cardiovascular disease

• Mahamat Y.K.
• Efimova V.P.
• Safarova A.F.
• Kobalava Zh.D.

Abstract

The aims - to study earLy Left ventricuLar injury in young patients with type 1 diabetes meLLitus without cardiovascuLar disease by speckLe tracking echocardiography and identify factors associated with dysfunction of gLobaL LongitudinaL systoLic deformation.

In 90 patients with type 1 diabetes meLLitus (DM) without cardiovascuLar disease (mean age was 29.1±8.2 years and mean diabetes duration 6,7) were studied earLy markers and associated cLinicaL signs of injury to the heart. It was found that subcLinicaL marker of heart injury in young patients with type 1 DM with preserved ejection fraction of the Left ventricLe is the reduction of gLobaL LongitudinaL systoLic function reveaLed by speckLe tracking Echocardiography. ReveaLed the association of aLbuminuria and GFR with LV dysfunction in patients with type 1 DM.

Keywords:type 1 diabetes mellitus, global longitudinal systolic function LV, speckle-tracking

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